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Panels › Hormone Panels › Progesterone

Progesterone

Significance
Progesterone is a steroid hormone derived from pregnenolone. In females, it is produced mostly by the ovaries. The production is higher during the luteal phase (second half) of the menstrual cycle and during pregnancy. It is low during the follicular phase (first half), before puberty, and after menopause. The primary biological function is to prepare the uterus to provide nutrition to the developing embryo during early pregnancy. Progesterone is also used for menopausal hormone replacement therapy and for women with infertility or frequent pregnancy loss. Measurement of progesterone is generally performed to evaluate infertility, corpus luteum function, basal body temperature (for monitoring ovulation), abnormal bleeding, placental function in pregnancy, and monitor some women on hormone replacement therapy.

Analysis
Determination of progesterone is performed by enzyme immunoassay.

Patient Preparation
Morning specimen is preferred.

Specimen requirements
Serum specimen - from a plain redtop or a redtop gel (tiger top) tube. Separate serum from cells after centrifugation, if a plain redtop tube is used. Provide patient age and gender. Minimum volume required is 1 mL. Specimen should be kept refrigerated where possible.

Shipping Instructions
Ship specimen at ambient temperatures. For long distance shipping, ship with ice packs.

Additional information
http://www.labtestsonline.org/understanding/analytes/progesterone/test.html